Neelakandha Mani: search on Z-Library

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1

An Efficient Intramolecular 1,3-Dipolar Cycloaddition Involving 2-(1,2-Dichlorovinyloxy)aryldiazomethanes: A One-Pot Synthesis of Benzofuropyrazoles from Salicylaldehydes

Sales, Zachary S., Mani, Neelakandha S.

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 164 KB

english, 2009

2

CuI-Catalyzed Amination of Arylhalides with Guanidines or Amidines: A Facile Synthesis of 1-H-2-Substituted Benzimidazoles

Deng, Xiaohu, McAllister, Heather, Mani, Neelakandha S.

Journal:

Journal of Organic Chemistry

Year:

2009

Language:

english

File:

PDF, 856 KB

english, 2009

3

An Efficient Route to 4-Aryl-5-pyrimidinylimidazoles via Sequential Functionalization of 2,4-Dichloropyrimidine

Deng, Xiaohu, Mani, Neelakandha S.

Journal:

Organic Letters

Year:

2006

Language:

english

File:

PDF, 78 KB

english, 2006

4

Synthesis of 4-Arylpiperidines from 1-Benzyl-4-piperidone: Application of the Shapiro Reaction and Alkenylsilane Cross-Coupling

Morrill, Christie, Mani, Neelakandha S.

Journal:

Organic Letters

Year:

2007

Language:

english

File:

PDF, 75 KB

english, 2007

5

ChemInform Abstract: CuI-Catalyzed Amination of Arylhalides with Guanidines or Amidines: A Facile Synthesis of 1-H-2-Substituted Benzimidazoles.

Xiaohu Deng, Heather McAllister, Neelakandha S. Mani

Journal:

Year:

2010

File:

PDF, 30 KB

2010

6

ChemInform Abstract: Reactivity-Controlled Regioselectivity: A Regiospecific Synthesis of 1,2-Disubstituted Benzimidazoles.

Xiaohu Deng, Neelakandha S. Mani

Journal:

Year:

2010

File:

PDF, 57 KB

2010

7

Reactivity-Controlled Regioselectivity: A Regiospecific Synthesis of 1,2-Disubstituted Benzimidazoles

Xiaohu Deng, Neelakandha S. Mani

Journal:

European Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 259 KB

english, 2010

8

Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: Synthesis and preliminary SAR analysis

Laurent Gomez, Michael D. Hack, Jiejun Wu, John J.M. Wiener, Hari Venkatesan, Alejandro Santillán Jr., Daniel J. Pippel, Neelakandha Mani, Brian J. Morrow, S. Timothy Motley, Karen Joy Shaw, Ronald Wo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 192 KB

english, 2007

9

Discovery and SAR of novel pyrazole-based thioethers as cathepsin S inhibitors: Part 1

Alice Lee-Dutra, Danielle K. Wiener, Kristen L. Arienti, Jing Liu, Neelakandha Mani, Michael K. Ameriks, Frank U. Axe, Damara Gebauer, Pragnya J. Desai, Steven Nguyen, Mike Randal, Robin L. Thurmond,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.79 MB

english, 2010

10

Synthesis of porphyrazine-octaamine, hexamine and diamine derivatives

Matthew J. Fuchter, L. Scott Beall, Sven M. Baum, Antonio Garrido Montalban, Efstathia G. Sakellariou, Neelakandha S. Mani, Todd Miller, Benjamin J. Vesper, Andrew J.P. White, David J. Williams, Antho

Journal:

Year:

2005

Language:

english

File:

PDF, 606 KB

english, 2005

11

Efficient synthesis of an androgen receptor modulator

Neelakandha S. Mani, Jyun-Hung Chen, James P. Edwards, Min Wu, Penghui Chen, Robert I. Higuchi

Journal:

Tetrahedron Letters

Year:

2008

Language:

english

File:

PDF, 103 KB

english, 2008

12

Carboxylation reaction of a highly functionalized vinylic anion: a case of unexpected stability and reactivity

Laurent Gomez, Jiejun Wu, Neelakandha S. Mani, Sudip Basu, Josef Moravek, J. Guy Breitenbucher

Journal:

Tetrahedron Letters

Year:

2010

Language:

english

File:

PDF, 294 KB

english, 2010

13

Synthesis of novel chiral macrocycles: crown ethers derived from D-glucose

Neelakandha S. Mani, Puthuparambil P. Kanakamma

Journal:

Tetrahedron Letters

Year:

1994

Language:

english

File:

PDF, 231 KB

english, 1994

14

An efficient synthetic route to chiral 4-alkyl-1,2,3,4-tetrahydroquinolines: enantioselective synthesis of (R)-4-ethyl-1,2,3,4-tetrahydroquinoline

Neelakandha S. Mani, Min Wu

Journal:

Tetrahedron: Asymmetry

Year:

2000

Language:

english

File:

PDF, 75 KB

english, 2000

15

An efficient synthesis of substituted benzene-1,2-dicarboxaldehydes

Peter C. Zhu, Der-Haw Wang, Kaitao Lu, Neelakandha Mani

Journal:

Science China Chemistry

Year:

2007

Language:

english

File:

PDF, 455 KB

english, 2007

16

Boron trifluoride etherate-assisted ring opening of ethylene oxide by a chiral organolithium: enantioselective synthesis of (R)-N-Boc-2-(2-hydroxyethyl)pyrrolidine

Xiaohu Deng, Neelakandha S. Mani

Journal:

Tetrahedron: Asymmetry

Year:

2005

Language:

english

File:

PDF, 121 KB

english, 2005

17

Direct, Metal-Free Amination of Heterocyclic Amides/Ureas with NH-Heterocycles and N-Substituted Anilines in POCl3

Deng, Xiaohu, Roessler, Armin, Brdar, Ivana, Faessler, Roger, Wu, Jiejun, Sales, Zachary S., Mani, Neelakandha S.

Journal:

Journal of Organic Chemistry

Year:

2011

Language:

english

File:

PDF, 2.04 MB

english, 2011

18

A Practical Synthesis of Regioisomeric 6- and 7-Methoxytetrahydro-3-benzazepines

Liang, Jimmy T., Liu, Jing, Shireman, Brock T., Tran, Vi, Deng, Xiaohu, Mani, Neelakandha S.

Journal:

Organic Process Research & Development

Year:

2010

Language:

english

File:

PDF, 565 KB

english, 2010

19

Reaction of N-Monosubstituted Hydrazones with Nitroolefins: A Novel Regioselective Pyrazole Synthesis

Deng, Xiaohu, Mani, Neelakandha S.

Journal:

Organic Letters

Year:

2006

Language:

english

File:

PDF, 187 KB

english, 2006

20

Serendipitous desymmetrisation during porphyrazine synthesis: an X-ray crystallographic study of 2,3,7,8,12,13,17,18-octakis(dimethylamino)-2-secoporphyrazine-2,3-dione

Mani, Neelakandha S., Beall, L. Scott, White, Andrew J. P., Williams, David J., Barrett, Anthony G. M., Hoffman, Brian M.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1994

Language:

english

File:

PDF, 217 KB

english, 1994

21

Seco-Porphyrazines: Synthetic, Structural, and Spectroscopic Investigations

Montalban, Antonio Garrido, Lange, Steven J., Beall, L. Scott, Mani, Neelakandha S., Williams, David J., White, Andrew J. P., Barrett, Anthony G. M., Hoffman, Brian M.

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 178 KB

english, 1997

22

Discovery of 6-N,N-Bis(2,2,2-trifluoroethyl)amino- 4-trifluoromethylquinolin-2(1H)-one as a Novel Selective Androgen Receptor Modulator#

van Oeveren, Arjan, Motamedi, Mehrnouch, Mani, Neelakandha S., Marschke, Keith B., López, Francisco J., Schrader, William T., Negro-Vilar, Andrés, Zhi, Lin

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 203 KB

english, 2006

23

Reactions between Weinreb Amides and 2-Magnesiated Oxazoles: A Simple and Efficient Preparation of 2-Acyl Oxazoles

Pippel, Daniel J., Mapes, Christopher M., Mani, Neelakandha S.

Journal:

Journal of Organic Chemistry

Year:

2007

Language:

english

File:

PDF, 86 KB

english, 2007

24

Oxidation of 4-Halo-2-nitrotoluene with Tetrabutylammonium Permanganate in Pyridine: Development and Safety Evaluation

Deng, Xiaohu, Stefanick, Stephen, Pippel, Marna C. W., Mani, Neelakandha S.

Journal:

Organic Process Research & Development

Year:

2006

Language:

english

File:

PDF, 222 KB

english, 2006

25

A facile, environmentally benign sulfonamide synthesis in water

Deng, Xiaohu, Mani, Neelakandha S.

Journal:

Green Chemistry

Year:

2006

Language:

english

File:

PDF, 229 KB

english, 2006

26

Protecting-group-free synthesis of a dual CCK1/CCK2 receptor antagonist

Liu, Jing, Deng, Xiaohu, Fitzgerald, Anne E., Sales, Zachary S., Venkatesan, Hariharan, Mani, Neelakandha S.

Journal:

Organic & Biomolecular Chemistry

Year:

2011

Language:

english

File:

PDF, 316 KB

english, 2011

27

Facile Assembly of Fused Benzo[4,5]furo Heterocycles

Liu, Jing, Fitzgerald, Anne E., Mani, Neelakandha S.

Journal:

Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 108 KB

english, 2008

28

Porphyrazines and Norphthalocyanines Bearing Nitrogen Donor Pockets: Metal Sensor Properties

Beall, L. Scott, Mani, Neelakandha S., White, Andrew J. P., Williams, David J., Barrett, Anthony G. M., Hoffman, Brian M.

Journal:

Journal of Organic Chemistry

Year:

1998

Language:

english

File:

PDF, 327 KB

english, 1998

29

Scale-Up Synthesis of a TRPV1 Antagonist Featuring a Facile Thiazolo[5,4- d ]pyrimidine Formation

Liu, Jing, Fitzgerald, Anne E., Lebsack, Alec D., Mani, Neelakandha S.

Journal:

Organic Process Research & Development

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

30

Convergent Synthesis of a 5HT 7 /5HT 2 Dual Antagonist

Liang, Jimmy T., Deng, Xiaohu, Mani, Neelakandha S.

Journal:

Organic Process Research & Development

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

31

First, Second, and Third Generation Scalable Syntheses of Two Potent H 3 Antagonists

Pippel, Daniel J., Mills, John E., Pandit, Chennagiri R., Young, Lana K., Zhong, Hua M., Villani, Frank J., Mani, Neelakandha S.

Journal:

Organic Process Research & Development

Year:

2011

Language:

english

File:

PDF, 1.27 MB

english, 2011

32

Strategies of synthesis based on cyclohexadienes: part 3. A novel route to macrolide aromatic polyketides

Birch, Arthur J., Mani, Neelakandha S., Rao, G. S. R. Subba

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1990

Language:

english

File:

PDF, 713 KB

english, 1990

33

Syntheses based on cyclohexadienes. Part 2. Convenient synthesis of 6-alkylsalicylates, 6-alkyl-2,4-dihydroxybenzoate, and 2,5-dialkylresorcinols

Kanakam, Charles C., Mani, Neelakandha S., Ramanathan, Halasya, Rao, G. S. R. Subba

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1989

Language:

english

File:

PDF, 1006 KB

english, 1989

34

Regioselective Synthesis of 1,3,5-Tri- and 1,3,4,5-Tetrasubstituted Pyrazoles from N -Arylhydrazones and Nitroolefins

Deng, Xiaohu, Mani, Neelakandha S.

Journal:

Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 134 KB

english, 2008

35

High-Yielding Syntheses of 1-Piperidin-4-yl Butyro- and Valerolactams through a Tandem Reductive Amination−Lactamization (Reductive Lactamization)

Mapes, Christopher M., Mani, Neelakandha S.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 89 KB

english, 2007

36

Oxysterols direct B-cell migration through EBI2

Liu, Changlu, Yang, Xia V., Wu, Jiejun, Kuei, Chester, Mani, Neelakandha S., Zhang, Li, Yu, Jingxue, Sutton, Steven W., Qin, Ning, Banie, Homayon, Karlsson, Lars, Sun, Siquan, Lovenberg, Timothy W.

Journal:

Year:

2011

Language:

english

File:

PDF, 690 KB

english, 2011

37

A Scalable Synthesis of a Histamine H 3 Receptor Antagonist

Mani, Neelakandha S., Jablonowski, Jill A., Jones, Todd K.

Journal:

Journal of Organic Chemistry

Year:

2004

Language:

english

File:

PDF, 83 KB

english, 2004

38

Discovery of a Potent, Orally Active, Nonsteroidal Androgen Receptor Agonist: 4-Ethyl-1,2,3,4-tetrahydro-6- (trifluoromethyl)-8-pyridono[5,6- g ]- quinoline (LG121071)

Hamann, Lawrence G., Mani, Neelakandha S., Davis, Robert L., Wang, Xiao-Ning, Marschke, Keith B., Jones, Todd K.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 62 KB

english, 1999

39

Convenient Preparation of Glycosyl Bromides

Mani, Neelakandha S., Kanakamma, Puthuparambil P.

Journal:

Synthetic Communications

Year:

1992

Language:

english

File:

PDF, 201 KB

english, 1992

40

Synthesis and characterisation of porphyrazinoctamine derivatives: X-ray crystallographic studies of [2,3,7,8,12,13,17,18-octakis(dibenzylamino)- porphyrazinato]magnesium(II) and {2,3,7,8,12,13,17,18-octakis[allyl(benzyl)amino]- porphyrazinato} nickel(II)

Mani, Neelakandha S., Beall, L. Scott, Miller, Todd, Anderson, Oren P., Hope, H�kon, Parkin, Sean R., Williams, David J., Barrett, Anthony G. M., Hoffman, Brian M.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1994

Language:

english

File:

PDF, 292 KB

english, 1994

41

Base-Mediated Reaction of Hydrazones and Nitroolefins with a Reversed Regioselectivity: A Novel Synthesis of 1,3,4-Trisubstituted Pyrazoles

Deng, Xiaohu, Mani, Neelakandha S.

Journal:

Organic Letters

Year:

2008

Language:

english

File:

PDF, 107 KB

english, 2008

42

Addition of Grignard Reagents to Quinolinium Salts: Evidence for a Unique Redox Reaction between a 1,4- and a 1,2-Dihydroquinoline

Mani, Neelakandha S., Chen, Penghui, Jones, Todd K.

Journal:

Journal of Organic Chemistry

Year:

1999

Language:

english

File:

PDF, 59 KB

english, 1999

43

Expedient Reductive Amination of Aldehyde Bisulfite Adducts

Pandit, Chennagiri, Mani, Neelakandha

Journal:

Year:

2009

Language:

english

File:

PDF, 103 KB

english, 2009

44

Regioselective Synthesis of 4-Nitro- or 4-Chloro-Tetrasubstituted Pyrazoles from Hydrazones and β-Halo-β-nitrostyrenes

Deng, Xiaohu, Liang, Jimmy T., Mani, Neelakandha S.

Journal:

European Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 813 KB

english, 2014

45

A Concise Synthesis of (+)-Cerulenin from a Chiral Oxiranyllithium

Mani, Neelakandha S., Townsend, Craig A.

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 214 KB

english, 1997

46

Practical Synthesis of a Cathepsin S Inhibitor: Route Identification, Purification Strategies, and Serendipitous Discovery of a Crystalline Salt Form

Deng, Xiaohu, Liang, Jimmy T., Peterson, Matthew, Rynberg, Raymond, Cheung, Eugene, Mani, Neelakandha S.

Journal:

Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 4.86 MB

english, 2010

47

A Step-Economical Route to Fused 1,2,3-Triazoles via an Intramolecular 1,3-Dipolar Cycloaddition between a Nitrile and an in Situ Generated Aryldiazomethane

Mani, Neelakandha S., Fitzgerald, Anne E.

Journal:

Journal of Organic Chemistry

Year:

2014

Language:

english

File:

PDF, 438 KB

english, 2014

48

Stereoselective Synthesis of Z -α-Aryl-α,β-unsaturated Esters

Mani, Neelakandha S., Mapes, Christopher M., Wu, Jiejun, Deng, Xiaohu, Jones, Todd K.

Journal:

Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 68 KB

english, 2006

49

Practical and Scalable Synthesis of a Selective CCK 1 Receptor Antagonist

Mapes, Christopher M., Mani, Neelakandha S., Deng, Xiaohu, Pandit, Chennagiri R., McClure, Kelly J., Pippel, Marna C. W., Sehon, Clark A., Gomez, Laurent, Shinde, Shirin, Breitenbucher, J. Guy, Jones,

Journal:

Journal of Organic Chemistry

Year:

2010

Language:

english

File:

PDF, 872 KB

english, 2010

50

A Practical Synthesis of Enantiopure 7-Alkoxy-4-aryl-tetrahydroisoquinoline, a Dual Serotonin Reuptake Inhibitor/Histamine H 3 Antagonist

Deng, Xiaohu, Liang, Jimmy T., Liu, Jing, McAllister, Heather, Schubert, Carsten, Mani, Neelakandha S.

Journal:

Organic Process Research & Development

Year:

2007

Language:

english

File:

PDF, 333 KB

english, 2007